Cinnamic acids and derivatives
Medchemexpress LLC Trans-Cinnamic acid | 140-10-3 | 148.16 | 500 MG
Trans-Cinnamic acid is a natural antimicrobial that demonstrates a minimal inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen A. sobria, SY-AS1.
- Natural antimicrobial agent.
- Exhibits moderate inhibition against various fish pathogens.
- More effective on bacteria when the pH of the culture media is not neutralized.
- For research use only.
Apexbio Technology LLC Sodium ferulic 24276-84-4 500mg
Sodium ferulic (CAS 24276-84-4) is a small molecule inhibitor targeting fibroblast growth factor receptors specifically FGFR1 and FGFR2 It demonstrates inhibitory activity with IC50 values of 3 78 M for FGFR1 and 12 5 M for FGFR2 At the cellular level sodium ferulic suppresses intracellular signaling pathways involved in cell proliferation This compound is utilized in biomedical research to investigate signaling mechanisms and to assess therapeutic potential in disease models such as cancer
Medchemexpress LLC 4-methylcinnamic acid | 1866-39-3 | MFCD00002697 | 99.6% | 162.19 | C10H10O2 | 1 ML
4-methylcinnamic acid is a cinnamic acid derivative used in research with reported antifungal activity. It is supplied for in vitro and in vivo studies and is provided as powder or concentrated stock solutions with guidance for formulation and storage.
- Cas number 1866-39-3.
- Molecular formula C10H10O2.
- Molecular weight 162.19 g/mol.
- Purity approximately 99.6%.
- Available as powder and in-solvent preparations.
- Solvent guidance: DMSO for high-concentration stocks.
- Stock preparation guidance for 1, 5, and 10 mM solutions from mg quantities.
- Storage recommendations: powder and in-solution temperature ranges with multi-year stability.
Medchemexpress LLC 3-Methylcinnamic acid | 3029-79-6 | 99.8% | C10H10O2 | 25 G
3-Methylcinnamic acid is a drug intermediate for the synthesis of various active compounds. This product is intended for research use only and is not sold to patients. It typically appears as a white to off-white solid.
- Drug intermediate for synthesis of various active compounds
- For research use only
- Appears as a white to off-white solid
- Molecular weight of 162.19
- Powder storage: -20°C for 3 years or 4°C for 2 years
- In solvent storage: -80°C for 6 months or -20°C for 1 month
Pfaltz & Bauer 2 4-Dimethoxycinnamic Acid 97 25G | 6972-61-8
2 4-Dimethoxycinnamic Acid 97 25G | 6972-61-8
Medchemexpress LLC 2-Methoxycinnamic acid | 6099-03-2 | 178.18 | 1 ML
2-Methoxycinnamic acid is a noncompetitive inhibitor of tyrosinase. It is for research use only.
- Purity: 99.94%
- Appearance: Solid, white to off-white
- Structure classification: Phenylpropanoids, Simple phenylpropanols
- Initial source: Plants (*Pulsatilla chinensis* (Bunge) Regel)
- Solubility (In Vitro): 100 mg/mL (561.23 mM) in DMSO (requires ultrasonication)
- Solubility (In Vivo): ≥ 2.5 mg/mL (14.03 mM) in 10% DMSO, 40% PEG300, 5% Tween-80, 45% Saline (clear solution) or in 10% DMSO, 90% Corn Oil (clear solution)
Selleck Chemical LLC Ferulic acid methyl ester S5451-25mg
Ferulic acid methyl ester (Methyl Ferulate Methyl 4 -hydroxy-3 -methoxycinnamate) is a lipophilic derivative of ferulic acid which is a hydroxycinnamic acid that is abundant in plants It shows the strongest antioxidant activity and can protect against inflammation and cancer
Medchemexpress LLC Lassbio-1135 | 852453-71-5 | 99.1% | C18H14N4 | 10MG
LASSBio-1135 is an orally active TRPV1 antagonist and anti-inflammatory/analgesic research compound. It shows moderate inhibition of human PGHS-2 (IC50 = 18.5 μM) and has demonstrated in vivo efficacy reversing capsaicin-induced thermal hyperalgesia and reducing carrageenan-induced paw edema. The material is supplied as a white to off-white solid with reported high purity and recommended low-temperature storage for stability.
- orally active TRPV1 antagonist with anti-inflammatory and analgesic activity
- moderate inhibition of human PGHS-2 (IC50 = 18.5 μM)
- demonstrated in vivo efficacy in pain and inflammation models
- high purity solid, white to off-white appearance
- recommended storage at low temperatures for long-term stability
Medchemexpress LLC 2-Hydroxycinnamic acid | 614-60-8 | CB1140462 | 99.9% | 164.16 | 5 G
2-Hydroxycinnamic acid is a phenolic acid possessing antimicrobial and antioxidant properties. It exhibits antimicrobial activity against Staphylococcus aureus and has shown to not be susceptible to drug resistance. Additionally, 2-Hydroxycinnamic acid demonstrates inhibitory effects on the infection of HIV/SARS-CoV S pseudovirus, with an IC50 of 0.3 mM. It also has neuroprotective and antitumor activities.
- Possesses antimicrobial properties.
- Has antioxidant properties.
- Exhibits antimicrobial activity against Staphylococcus aureus.
- Not susceptible to drug resistance.
- Demonstrates inhibitory effects on the infection of HIV/SARS-CoV S pseudovirus.
- Has neuroprotective activities.
- Has antitumor activities.
Medchemexpress LLC 4-nitrocinnamic acid | 619-89-6 | MFCD00007381 | 99.9% | 193.16 g/mol | C9H7NO4 | 25 G
4-Nitrocinnamic acid is a nitro-substituted cinnamic acid used as a research reagent and synthetic building block. It is applied in organic synthesis and materials research and is supplied with analytical characterization to support laboratory use.
- High purity for reliable experimental results.
- Suitable as a building block in organic synthesis.
- Soluble in common organic solvents for easy handling.
- Characterized by CAS 619-89-6 and molecular formula C9H7NO4.
- Supplied in controlled pack sizes for laboratory use.
Medchemexpress LLC 1-(2-dimethylaminoethyl)-1,2,3,4-tetrahydro-2-methylcarbazole hydrochloride | 54-84-2 | MFCD00055609 | 99.5% | 376.9 g/mol | C20H25ClN2OS | 1 ML
Cinanserin hydrochloride is the hydrochloride salt of cinanserin, supplied for research use as a 10 mM solution in DMSO (1 mL) and as solid quantities. It functions as a 5-HT2 receptor antagonist in pharmacological and biochemical studies and is provided with supporting documentation for quality control.
- Provided as 10 mM solution in DMSO (1 mL) and as solid pack sizes.
- High purity suitable for biochemical and pharmacological assays.
- Accompanied by a datasheet and certificate of analysis.
- Used as a 5-HT2 receptor antagonist in research applications.
- CAS number 54-84-2 for unambiguous chemical identification.
- Molecular weight 376.9 g/mol.
Selleck Chemical LLC AG 494
AG-494 a member of the tyrphostin family of tyrosine kinase inhibitors is a potent inhibitor of EGF receptor autophosphorylation (IC50 1 2 M) and EGF-dependent cell growth (IC50 6 M)
Medchemexpress LLC Tyrphostin AG 112 | 144978-82-5 | 98.3% | 236.23 | 25 MG
Tyrphostin AG 112 is an EGFR phosphorylation inhibitor intended for research use only. It inhibits EGFR in human A431 cells with an IC50 of 0.1 μM.
- EGFR phosphorylation inhibitor
- Inhibits EGFR in human A431 cells with an IC50 of 0.1 μM
- For research use only
- Appears as a light yellow to yellow solid
Medchemexpress LLC Entacapone | 130929-57-6 | MFCD00866580 | 99.2% | 305.29 g/mol | C14H15N3O5 | 5 MG
Entacapone (Standard) is an analytical reference standard of entacapone provided for research and analytical use. Supplied in small quantitative sizes suitable for assay development, method validation, and quality control, the product includes batch documentation and a Certificate of Analysis reporting high purity. It is used as a reference material in studies involving COMT inhibition and related biochemical assays.
- Analytical standard for assay development and method validation.
- Available in small sizes, including a 5 mg vial.
- Certified purity approximately 99.2% (COA available).
- Useful for quality control and reference material applications.
- Molecular formula C14H15N3O5; molecular weight 305.29 g/mol.
Apexbio Technology LLC Tyrphostin 9 10537-47-0 25mg
Tyrphostin 9 is a selective inhibitor targeting platelet-derived growth factor receptor (PDGFR) and epidermal growth factor receptor (EGFR) It inhibits PDGFR autophosphorylation with an IC50 of approximately 2 5 M and EGFR kinase activity (IC50 around 460 M) Additionally Tyrphostin 9 inhibits platelet-derived growth factor (PDGF)-stimulated smooth muscle cell proliferation (IC50 approximately 40 nM) as well as phosphorylation of phospholipase C gamma (PLC IC50 2 5 M) and induction of PDGF-dependent c-fos expression In research models Tyrphostin 9 has been utilized to study receptor-mediated signal transduction and vascular injury-related neointimal proliferation processes